Bedaquiline is a topic covered in the Johns Hopkins ABX Guide.

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INDICATIONS

FDA

  • Treatment of pulmonary MDR TB (resistant to at least INH and rifampin) in combination with other active antimycobacterial agents (minimum of four-drug treatment regimen).
    • Bedaquiline should not be used for the treatment of latent TB, or drug-sensitive TB.

NON-FDA APPROVED USES

  • On a case-by-case basis bedaquiline can be considered in extra-pulmonary TB, children, pregnant women, and HIV-infected patients when an effective anti-TB cannot be provided otherwise (CDC recommendation)

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Last updated: January 3, 2014