Ureaplasma urealyticum
Ureaplasma urealyticum is a topic covered in the Johns Hopkins ABX Guide.
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MICROBIOLOGY
- Among the smallest of bacteria; it lacks a cell wall [Fig 1].
- Member of Mycoplasmataceae family.
- May be normal component of male/female genital flora.
- Found normally on genital mucosal surfaces in the majority of sexually active adults.
- Media for growth must contain cholesterol (tissue culture conditions needed); organism hydrolyzes urea--hence its name.
- Usually sub-cultured to blood agar plate for identification. Ureaplasma colonies are of a pinpoint character.
- 17 species recognized from humans, with 4 as most often implicated: usually species can only distinguish in clinical samples by PCR.
- Ureaplasma parvum (Up): most commonly isolated, considered vaginal commensal.
- Ureaplasma urealyticum (Uu): considered most virulent, especially in urethritis afflicting men, although one large study found a lack of association with symptoms[4].
- Association with other disease entities such as PID is less robust.
- Ureaplasma parvum (Up): most commonly isolated, considered vaginal commensal.
-- To view the remaining sections of this topic, please log in or purchase a subscription --
MICROBIOLOGY
- Among the smallest of bacteria; it lacks a cell wall [Fig 1].
- Member of Mycoplasmataceae family.
- May be normal component of male/female genital flora.
- Found normally on genital mucosal surfaces in the majority of sexually active adults.
- Media for growth must contain cholesterol (tissue culture conditions needed); organism hydrolyzes urea--hence its name.
- Usually sub-cultured to blood agar plate for identification. Ureaplasma colonies are of a pinpoint character.
- 17 species recognized from humans, with 4 as most often implicated: usually species can only distinguish in clinical samples by PCR.
- Ureaplasma parvum (Up): most commonly isolated, considered vaginal commensal.
- Ureaplasma urealyticum (Uu): considered most virulent, especially in urethritis afflicting men, although one large study found a lack of association with symptoms[4].
- Association with other disease entities such as PID is less robust.
- Ureaplasma parvum (Up): most commonly isolated, considered vaginal commensal.
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Last updated: December 9, 2019
Citation
Auwaerter, Paul G. "Ureaplasma Urealyticum." Johns Hopkins ABX Guide, The Johns Hopkins University, 2019. Johns Hopkins Guide, www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540617/all/Ureaplasma_urealyticum.
Auwaerter PG. Ureaplasma urealyticum. Johns Hopkins ABX Guide. The Johns Hopkins University; 2019. https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540617/all/Ureaplasma_urealyticum. Accessed January 28, 2023.
Auwaerter, P. G. (2019). Ureaplasma urealyticum. In Johns Hopkins ABX Guide. The Johns Hopkins University. https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540617/all/Ureaplasma_urealyticum
Auwaerter PG. Ureaplasma Urealyticum [Internet]. In: Johns Hopkins ABX Guide. The Johns Hopkins University; 2019. [cited 2023 January 28]. Available from: https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540617/all/Ureaplasma_urealyticum.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC
T1 - Ureaplasma urealyticum
ID - 540617
A1 - Auwaerter,Paul,M.D.
Y1 - 2019/12/09/
BT - Johns Hopkins ABX Guide
UR - https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540617/all/Ureaplasma_urealyticum
PB - The Johns Hopkins University
DB - Johns Hopkins Guide
DP - Unbound Medicine
ER -