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    Ureaplasma urealyticum

    Paul G. Auwaerter, M.D.
    Ureaplasma urealyticum is a topic covered in the Johns Hopkins ABX Guide.

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    MICROBIOLOGY

    • Among the smallest of bacteria; lacks a cell well. Member of Mycoplasmataceae family.
      • May be normal component of male/female genital flora.
      • Found normally on genital mucosal surfaces in majority of sexually active adults.
    • Media for growth must contain cholesterol (tissue culture conditions needed); organism hydrolyzes urea--hence its name.
      • Usually sub-cultured to blood agar plate for identification. Ureaplasma colonies are of a pinpoint character.
    • 17 species recognized from humans, with 4 as most often implicated: usually species can only distinguish in clinical samples by PCR.
      • Ureaplasma parvum (Up): most commonly isolated, considered vaginal commensal.
      • Ureaplasma urealyticum (Uu): considered most virulent, especially in urethritis afflicting men, although one large study found a lack of association with symptoms[2].
        • Association with other disease entities such as PID is less robust.

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    Last updated: April 5, 2016

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    TY - ELEC T1 - Ureaplasma urealyticum ID - 540617 A1 - Auwaerter,Paul,M.D. Y1 - 2016/04/05/ BT - Johns Hopkins ABX Guide UR - https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540617/all/Ureaplasma_urealyticum PB - The Johns Hopkins University DB - Johns Hopkins Guide DP - Unbound Medicine ER -