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Artemether/Lemefantrine

Edina Avdic, Pharm.D.
Artemether/Lemefantrine is a topic covered in the Johns Hopkins ABX Guide.

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INDICATIONS

FDA

  • Treatment of acute, uncomplicated malaria infections due to Plasmodium falciparum in patients with ≥ 5 kg.
    • Manufacturer does not recommend use for the treatment of severe malaria or the prevention of P. falciparum malaria.
    • Most recent CDC guidelines recommend artemether/lumefantrine use for the treatment of severe malaria following administration of IV artesunate or while waiting for IV artesunate to arrive from CDC (see CDC website)

NON-FDA APPROVED USES

  • Treatment of severe malaria due to P. falciparum following administration of IV artesunate or while awaiting for IV artesunate to arrive from CDC.
  • Treatment of uncomplicated P. vivax malaria (2015 WHO recommendations)[2].

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Last updated: June 6, 2019

Citation

Avdic, Edina. "Artemether/Lemefantrine." Johns Hopkins ABX Guide, The Johns Hopkins University, 2019. Johns Hopkins Guide, www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540604/all/Artemether_Lemefantrine.
Avdic E. Artemether/Lemefantrine. Johns Hopkins ABX Guide. The Johns Hopkins University; 2019. https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540604/all/Artemether_Lemefantrine. Accessed July 17, 2019.
Avdic, E. (2019). Artemether/Lemefantrine. In Johns Hopkins ABX Guide. Available from https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540604/all/Artemether_Lemefantrine
Avdic E. Artemether/Lemefantrine [Internet]. In: Johns Hopkins ABX Guide. The Johns Hopkins University; 2019. [cited 2019 July 17]. Available from: https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540604/all/Artemether_Lemefantrine.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC T1 - Artemether/Lemefantrine ID - 540604 A1 - Avdic,Edina,Pharm.D. Y1 - 2019/06/06/ BT - Johns Hopkins ABX Guide UR - https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540604/all/Artemether_Lemefantrine PB - The Johns Hopkins University DB - Johns Hopkins Guide DP - Unbound Medicine ER -