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- CDC INDICATIONS: inadvertent inoculation (extensive lesions or some ocular implantations), eczema vaccinatum, generalized vaccinia (if severe or recurrent), progressive vaccinia
- NOT RECOMMENDED: prophylaxis against smallpox vaccination adverse event, accidental implantation (mild instances), generalized vaccinia (mild or limited - most instances), eerythema multiforme, encephalitis post-vaccination (not effective), vaccinia keratitis (may produce severe corneal opacities).