Vibrio cholerae is a topic covered in the Johns Hopkins ABX Guide.

To view the entire topic, please or purchase a subscription.

Official website of the Johns Hopkins Antibiotic (ABX), HIV, Diabetes, and Psychiatry Guides, powered by Unbound Medicine. Johns Hopkins Guide App for iOS, iPhone, iPad, and Android included. Explore these free sample topics:

Johns Hopkins Guides

-- The first section of this topic is shown below --

MICROBIOLOGY

  • Aerobic, Gram-negative, comma-shaped bacillus.
    • Cary Blair media suggested for transport.
    • Selective thiosulfate–citrate–bile salts agar (TCBS) best used for culture.
  • Water-borne pathogen, humans usually acquire infection through ingesting contaminated water or food. Countries may have endemic infection (ongoing continuously often with spikes during rainy season) or epidemics.
    • V., cholerae serogroup O1, biotype El Tor, originated in Asia but has caused infection (seventh cholera pandemic) throughout Africa and South America for ~43 yrs.
    • Newer serogroup, O139 described in SE Asia in 1992 now endemic.
  • Isolates described with resistance to ampicillin, tetracycline, ampicillin, aminoglycosides, sulfonamides, fluoroquinolones and trimethoprim.
  • Non-01 V. cholerae strains (also water-borne, may be non-toxigenic) can rarely cause non-diarrheal illness such as bacteremia and wound infections especially in cirrhotics. Infections may be from fresh or brackish waters.

-- To view the remaining sections of this topic, please or purchase a subscription --

Last updated: April 5, 2016