Varicella-zoster virus is a topic covered in the Johns Hopkins ABX Guide.

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MICROBIOLOGY

  • DNA virus member of Herpesviridae family.
  • Humans only known reservoir.
  • Primary infection spread by respiratory route with viral latency established in nerves.
    • Latent VZV found in dorsal root ganglia and cranial nerve ganglia.
  • By adulthood 90-95% infected (pre-vaccine era).

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Last updated: March 24, 2015