Tobramycin is a topic covered in the Johns Hopkins ABX Guide.

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INDICATIONS

FDA

  • UTI
  • Septicemia, including serious central nervous system infections (use in combination)
  • Lower respiratory tract infections (use in combination)
  • Complicated urinary tract infections
  • Intra-abdominal infections, including peritonitis (use in combination)
  • Skin, bone, and skin structure infections (use in combination)
  • Management of cystic fibrosis, with P. aeruginosa (as TOBI inhalation)
  • Treatment of ocular infections (uncomplicated conjunctivitis-ophthalmic solution)

NON-FDA APPROVED USES

  • Pneumonia, hospital-acquired (in combination with a beta-lactam, beta-lactam/beta-lactamase inhibitor, or a third/fourth-generation cephalosporin)
  • Pseudomonal infections (in combination with a beta-lactam, beta-lactam/beta-lactamase inhibitor, carbapenem or a third/fourth-generation cephalosporin)

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Last updated: November 2, 2015