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- Complicated skin and skin structure infections caused by susceptible Gram-positive bacteria (S. aureus including MRSA, S. pyogenes, other Strep species [S. agalactiae, S. anginosusgroup], or vancomycin sensitive E. faecalis).
- HAP and VAP caused by susceptible isolates of S. aureus.
- It should be reserved for use when alternative agents are not suitable.