Telavancin is a topic covered in the Johns Hopkins Antibiotic (ABX) Guide.

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  • Complicated skin and skin structure infections caused by susceptible Gram-positive bacteria (S. aureus including MRSA, S. pyogenes, other Strep species [S. agalactiae, S. anginosusgroup], or vancomycin sensitive E. faecalis).
  • HAP and VAP caused by susceptible isolates of S. aureus.
    • It should be reserved for use when alternative agents are not suitable.


  • S. aureus bacteremia and right-sided endocarditis randomized trial comparing telavancin with standard therapy is under way (NCT02208063)

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Last updated: December 14, 2015