Sulfadiazine

Paul A. Pham, Pharm.D., John G. Bartlett, M.D.

Sulfadiazine is a topic covered in the Johns Hopkins ABX Guide.

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INDICATIONS

FDA

CNS and ocular toxoplasmosis (in combination with pyrimethamine)
Nocardia
Malaria due to chloroquine-resistant P. falciparum (in combination with quinine and pyrimethamine)
UTI (also FDA indicated for pyelonephritis, but generally reserved for uncomplicated UTI, trimethoprim/sulfamethoxazole [TMP/SMX] preferred)
FDA indicated, but not generally recommended: chancroid, trachoma, inclusion conjunctivitis
FDA indicated, but not generally recommended: prophylaxis of meningococcal meningitis when sulfonamide-sensitive group A strains are known to prevail, meningococcal meningitis, acute otitis media due to Haemophilus influenzae (in combination with PCN), prophylaxis against recurrences of rheumatic fever (alternative to penicillin), H. influenzae meningitis (in combination with streptomycin)

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Last updated: February 1, 2016

Citation

Pham, Paul A, and John G Bartlett. "Sulfadiazine." Johns Hopkins ABX Guide, The Johns Hopkins University, 2016. Johns Hopkins Guide, www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540528/all/Sulfadiazine.

Pham PA, Bartlett JG. Sulfadiazine. Johns Hopkins ABX Guide. The Johns Hopkins University; 2016. https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540528/all/Sulfadiazine. Accessed February 23, 2019.

Pham, P. A., & Bartlett, J. G. (2016). Sulfadiazine. In Johns Hopkins ABX Guide. Available from https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540528/all/Sulfadiazine

Pham PA, Bartlett JG. Sulfadiazine [Internet]. In: Johns Hopkins ABX Guide. The Johns Hopkins University; 2016. [cited 2019 February 23]. Available from: https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540528/all/Sulfadiazine

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TY - ELEC T1 - Sulfadiazine ID - 540528 A1 - Bartlett,John,M.D. AU - Pham,Paul,Pharm.D. Y1 - 2016/02/01/ BT - Johns Hopkins ABX Guide UR - https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540528/all/Sulfadiazine PB - The Johns Hopkins University DB - Johns Hopkins Guide DP - Unbound Medicine ER -