Official website of the Johns Hopkins Antibiotic (ABX), HIV, Diabetes, and Psychiatry Guides, powered by Unbound Medicine. Johns Hopkins Guide App for iOS, iPhone, iPad, and Android included. Explore these free sample topics:
-- The first section of this topic is shown below --
- Helminthic parasite, common worldwide but especially in warmer climes.
- S. stercoralis is the major pathogen.
- S. fuelleborni occasional human pathogen, described in Papua New Guinea and Africa.
- Larvae live in soil. Human infection by contact with contaminated soil.
- Filariform larvae penetrate skin and enter lymphatics → lung alveoli.
- Migration from lung to trachea to GI tract/small intestine.
- Females yield to parthenogenic reproduction with eggs that turn to rhabditiform larvae within the intestine.
- Cycle yields long-term infection in humans (years-decades, may be considered lifelong).
- Immunosuppression can yield increased organisms by result of auto-infection → hyperinfection [see life cycle Fig. 1], a potentially fatal condition.
- Larvae are typically seen ~1 month after exposure.