Splenic Abscess is a topic covered in the Johns Hopkins ABX Guide.

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  • Polymicrobial in up to 25% including anaerobes.
    • Given that most splenic abscesses are secondary to bacteremia or fungemia (e.g., associated with endocarditis, UTI, pancreatitis, GI tract, etc.), the likely pathogen(s) are determined by original focus.
  • Gram-negative bacilli, especially
  • Staphylococcus aureus
  • Streptococci
  • Enterococci
  • Anaerobes
  • Candida spp.
    • Neutropenia and chronic corticosteroid use predispose to candidal splenic abscesses.
    • Chronic disseminated candidiasis (formerly hepatosplenic candidiasis) often include frank candidal splenic abscesses.
  • Mycobacteria
    • Tuberculosis
  • Rare:

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Last updated: September 3, 2017