Splenic Abscess is a topic covered in the Johns Hopkins Antibiotic (ABX) Guide.

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  • Gram negative bacilli, especially E. coli and Salmonella spp.
  • Staphylococcus aureus
  • Streptococci and enterococci
  • Anaerobes
  • Candida spp.
    • Neutropenia and chronic corticosteroid use predispose to candida splenic abscesses.
    • Chronic disseminated candidiasis (formerly hepatosplenic candidiasis) often include frank candidal splenic abscesses.
  • Mycobacteria
  • Rarely, Brucella spp.
  • Polymicrobial in up to 25% including anaerobes.
  • Given that most splenic abscesses are secondary to bacteremia or fungemia (e.g., associated with endocarditis , UTI , pancreatitis, GI tract, etc.), the likely pathogen(s) are determined by original focus.

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Last updated: March 25, 2013