Rhinovirus
Rhinovirus is a topic covered in the Johns Hopkins ABX Guide.
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MICROBIOLOGY
- Single-strand, non-enveloped positive sense RNA virus; member of the Picornaviridae family of viruses.
- Over 105 serologic virus types. Human rhinovirus responsible for up to 0-80% of common colds.
- Species include RV-A (adults > children), RV-B (least common) and RV-C (new species, often more severe or disseminated in children)
- Rhinoviruses gain entry via the upper respiratory tract binding to ICAM-1 (intracellular adhesion molecule -1) receptors on epithelial cells lining the respiratory tract. Chemokines and cytokines cause inflammation as a consequence of viral infection causing local symptoms.
- Involvement of cell receptor believed to account for part of host effect and and pathogenesis.
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Last updated: February 1, 2016
Citation
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TY - ELEC
T1 - Rhinovirus
ID - 540476
A1 - Auwaerter,Paul,M.D.
Y1 - 2016/02/01/
BT - Johns Hopkins ABX Guide
UR - https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540476/all/Rhinovirus
PB - The Johns Hopkins University
DB - Johns Hopkins Guide
DP - Unbound Medicine
ER -