Johns Hopkins ABX Guide
Respiratory syncytial virus
MICROBIOLOGY
- Negative-sense, single-strand, enveloped RNA virus.
- There are two subtypes (A and B). The severity may be similar between the two viruses.
- The scientific name is human orthopneumovirus.
- A synonym is human respiratory syncytial virus (hRSV), sometimes shortened to just RSV.
- Member of the Pneumoviridae family and Orthopneumovirus genus.
- RSV fusion protein facilitates the fusion of the viral envelope with the host cell membrane. This protein is a target for vaccines and anti-viral agents.
- In this section, we will refer to the virus that infects humans as RSV (although human orthopneumovirus is the international committee on taxonomy of viruses preferred term).
- Transmission:
- There are no animal reservoirs for this virus.
- Spread via nasal or oral secretions, either directly via large droplets (and probably aerosolized particles) or indirectly through contact with contaminated hands and environmental surfaces (e.g. cribs, toys, doorknobs, tabletops)
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Last updated: November 11, 2022
Citation
Shoham, Shmuel. "Respiratory Syncytial Virus." Johns Hopkins ABX Guide, The Johns Hopkins University, 2022. Johns Hopkins Guides, www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540472/all/Respiratory_syncytial_virus.
Shoham S. Respiratory syncytial virus. Johns Hopkins ABX Guide. The Johns Hopkins University; 2022. https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540472/all/Respiratory_syncytial_virus. Accessed September 23, 2023.
Shoham, S. (2022). Respiratory syncytial virus. In Johns Hopkins ABX Guide. The Johns Hopkins University. https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540472/all/Respiratory_syncytial_virus
Shoham S. Respiratory Syncytial Virus [Internet]. In: Johns Hopkins ABX Guide. The Johns Hopkins University; 2022. [cited 2023 September 23]. Available from: https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540472/all/Respiratory_syncytial_virus.
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