Raltegravir
Raltegravir is a topic covered in the Johns Hopkins ABX Guide.
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INDICATIONS
FDA
FDA
- Treatment of HIV-1 infection in combination with other ARV agents in ART-experienced patients with evidence of HIV replication despite ongoing ART.
- Treatment of HIV-1 infection in combination with other ARV agents in ART-naive patients.
NON-FDA APPROVED USES
NON-FDA APPROVED USES
- HIV-1 nonoccupational postexposure prophylaxis (nPEP): 400 mg tablet twice daily for 28 days in combination with other antiretrovirals. Therapy should be initiated within 72 hours.
- HIV-1 occupational postexposure prophylaxis (oPEP): 400 mg twice daily for 4 weeks with concomitant emtricitabine/tenofovir. Therapy should be initiated as soon as possible after occupational exposure.
- Substitution for other ARV agents due to drug toxicity or intolerance in pts on a suppressive regimen
-- To view the remaining sections of this topic, please log in or purchase a subscription --
INDICATIONS
FDA
FDA
- Treatment of HIV-1 infection in combination with other ARV agents in ART-experienced patients with evidence of HIV replication despite ongoing ART.
- Treatment of HIV-1 infection in combination with other ARV agents in ART-naive patients.
NON-FDA APPROVED USES
NON-FDA APPROVED USES
- HIV-1 nonoccupational postexposure prophylaxis (nPEP): 400 mg tablet twice daily for 28 days in combination with other antiretrovirals. Therapy should be initiated within 72 hours.
- HIV-1 occupational postexposure prophylaxis (oPEP): 400 mg twice daily for 4 weeks with concomitant emtricitabine/tenofovir. Therapy should be initiated as soon as possible after occupational exposure.
- Substitution for other ARV agents due to drug toxicity or intolerance in pts on a suppressive regimen
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Last updated: February 12, 2022
Citation
Kilcrease, Christin. "Raltegravir." Johns Hopkins ABX Guide, The Johns Hopkins University, 2022. Johns Hopkins Guides, www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540471/all/Raltegravir.
Kilcrease C. Raltegravir. Johns Hopkins ABX Guide. The Johns Hopkins University; 2022. https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540471/all/Raltegravir. Accessed March 29, 2023.
Kilcrease, C. (2022). Raltegravir. In Johns Hopkins ABX Guide. The Johns Hopkins University. https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540471/all/Raltegravir
Kilcrease C. Raltegravir [Internet]. In: Johns Hopkins ABX Guide. The Johns Hopkins University; 2022. [cited 2023 March 29]. Available from: https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540471/all/Raltegravir.
* Article titles in AMA citation format should be in sentence-case
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