Pyrimethamine + sulfadoxine is a topic covered in the Johns Hopkins ABX Guide.

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INDICATIONS

FDA

  • No longer available in the U.S.
  • Prophylaxis and treatment of chloroquine-resistant malaria.
  • Malaria (acute) in combination with sulfadoxine and quinine in the treatment of chloroquine-resistant Plasmodium falciparum malaria.
    • Resistance prevalent worldwide (not recommended as a prophylactic agent for travelers to most areas).

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Last updated: January 27, 2016