Pseudomonas aeruginosa

Lisa A. Spacek, M.D., Ph.D., Khalil G. Ghanem, M.D.

Pseudomonas aeruginosa is a topic covered in the Johns Hopkins ABX Guide.

To view the entire topic, please sign in or purchase a subscription.

Official website of the Johns Hopkins Antibiotic (ABX), HIV, Diabetes, and Psychiatry Guides, powered by Unbound Medicine. Johns Hopkins Guide App for iOS, iPhone, iPad, and Android included. Explore these free sample topics:

Enterovirus

Kidney Transplantation

Raltegravir

Major Depressive Disorder

-- The first section of this topic is shown below --

MICROBIOLOGY

Gram-negative non-fermenting, motile bacillus; known for blue-green pus (due to pyocyanin and pyoverdin pigments).
Non-fastidious organism, it can inhabit a variety of environments including soil and water (hot tubs, sinks, water faucets, respirators, disinfectants and contact lens cleaning solutions). Produces biofilm, toxins and proteases.
Drug resistance mechanisms: multiple pathways include active efflux pumps, chromosomal and inducible beta-lactamases, acquired genes and plasmid-mediated ESBLs (TEM, SHV, CTX-M), and altered permeability. Loss of protein porin OprD results in resistance to carbapenems, specifically imipenem.[4]

-- To view the remaining sections of this topic, please sign in or purchase a subscription --

Last updated: April 10, 2016

Citation

Spacek, Lisa A, and Khalil G Ghanem. "Pseudomonas Aeruginosa." Johns Hopkins ABX Guide, The Johns Hopkins University, 2016. Johns Hopkins Guide, www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540457/all/Pseudomonas_aeruginosa.

Spacek LA, Ghanem KG. Pseudomonas aeruginosa. Johns Hopkins ABX Guide. The Johns Hopkins University; 2016. https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540457/all/Pseudomonas_aeruginosa. Accessed February 23, 2019.

Spacek, L. A., & Ghanem, K. G. (2016). Pseudomonas aeruginosa. In Johns Hopkins ABX Guide. Available from https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540457/all/Pseudomonas_aeruginosa

Spacek LA, Ghanem KG. Pseudomonas Aeruginosa [Internet]. In: Johns Hopkins ABX Guide. The Johns Hopkins University; 2016. [cited 2019 February 23]. Available from: https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540457/all/Pseudomonas_aeruginosa

* When formatting your citation, note that all book, journal, and database titles should be italicized* Article titles in AMA citation format should be in sentence-case

TY - ELEC T1 - Pseudomonas aeruginosa ID - 540457 A1 - Ghanem,Khalil,M.D. AU - Spacek,Lisa,M.D., Ph.D. Y1 - 2016/04/10/ BT - Johns Hopkins ABX Guide UR - https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540457/all/Pseudomonas_aeruginosa PB - The Johns Hopkins University DB - Johns Hopkins Guide DP - Unbound Medicine ER -