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- P. shigelloides is a facultative, anaerobic, Gram negative rod weakly related to the species of Enterobacteriaceae and Vibrionaceae.
- Previously known as Aeromonas shigelloides.
- Many reports linking organism to gastroenteritis, but remains controversial whether true human pathogen.
- Contamination of water, food sources reported.
- Rare reports of bacteremia or extra-gastrointestinal infections.
- Clinicians should recognize as a possible cause diarrhea or dysentery in proper epidemiological and clinical context.
- Distinguish from Shigella spp. by oxidase test; distinguished from Aeromonas by negative DNAse testing.
- Ubiquitous environmentally, it can be isolated from soil, fresh water, fish, shellfish and a wide range of animal species.
- Mechanism of diarrhea due to Plesiomonas shigelloides is unknown. It is capable of producing a cholera-like enterotoxin, thermostable enterotoxin, and also a thermolabile enterotoxin.