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- P. shigelloides is a facultative, anaerobic, Gram-negative rod weakly related to the species of Enterobacteriaceae and Vibrionaceae.
- Ubiquitous environmentally, it can be isolated from soil, usually fresh water, fish, shellfish and a wide range of animal species.
- Mechanism of diarrhea due to Plesiomonas shigelloides is unknown. It is capable of producing a cholera-like enterotoxin, thermostable enterotoxin, and also a thermolabile enterotoxin.
- Many isolates produce beta-lactamases.
- Usually susceptible to fluoroquinolones and carbapenems.