Necrotizing Fasciitis
Necrotizing Fasciitis is a topic covered in the Johns Hopkins ABX Guide.
To view the entire topic, please sign in or purchase a subscription.
Official website of the Johns Hopkins Antibiotic (ABX), HIV, Diabetes, and Psychiatry Guides, powered by Unbound Medicine. Johns Hopkins Guide App for iOS, iPhone, iPad, and Android included. Explore these free sample topics:
-- The first section of this topic is shown below --
PATHOGENS
- Some classify necrotizing fasciitis (NF) into Type I and Type II.
- Mixed aerobic-anaerobic bacteria [Type I]
- Group A Streptococcus (GAS, S. pyogenes, Type II)
- Thought to be the most common cause. CDC estimates ~ 700-1200 cases/yr annually since 2010.
- Certain Streptococcal strains are seen more frequently in NF, most commonly those that contain M protein types 1, 3, 12, and 28 (elaborating pyrogenic exotoxin A).
- May complicate routine varicella or zoster as superinfeciton.
- Other pathogens that may cause NF
- Other Streptococcal species
- Clostridium perfringens
- Staphylococcus aureus
- Vibrio vulnificus
- Aeromonas spp.
- Klebsiella spp.
- Pseudomonas aeruginosa
- Other: host of occasional bacterial pathogens implicated, Candida and Mucor spp. also rarely described.
-- To view the remaining sections of this topic, please sign in or purchase a subscription --
Last updated: August 9, 2019
Citation
Auwaerter, Paul G, and John G Bartlett. "Necrotizing Fasciitis." Johns Hopkins ABX Guide, The Johns Hopkins University, 2019. Johns Hopkins Guide, www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540378/all/Necrotizing_Fasciitis.
Auwaerter PG, Bartlett JG. Necrotizing Fasciitis. Johns Hopkins ABX Guide. The Johns Hopkins University; 2019. https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540378/all/Necrotizing_Fasciitis. Accessed August 19, 2019.
Auwaerter, P. G., & Bartlett, J. G. (2019). Necrotizing Fasciitis. In Johns Hopkins ABX Guide. Available from https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540378/all/Necrotizing_Fasciitis
Auwaerter PG, Bartlett JG. Necrotizing Fasciitis [Internet]. In: Johns Hopkins ABX Guide. The Johns Hopkins University; 2019. [cited 2019 August 19]. Available from: https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540378/all/Necrotizing_Fasciitis.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC
T1 - Necrotizing Fasciitis
ID - 540378
A1 - Auwaerter,Paul,M.D.
AU - Bartlett,John,M.D.
Y1 - 2019/08/09/
BT - Johns Hopkins ABX Guide
UR - https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540378/all/Necrotizing_Fasciitis
PB - The Johns Hopkins University
DB - Johns Hopkins Guide
DP - Unbound Medicine
ER -