Mycoplasma pneumoniae

Mycoplasma pneumoniae is a topic covered in the Johns Hopkins ABX Guide.

To view the entire topic, please or purchase a subscription.

Official website of the Johns Hopkins Antibiotic (ABX), HIV, Diabetes, and Psychiatry Guides, powered by Unbound Medicine. Johns Hopkins Guide App for iOS, iPhone, iPad, and Android included. Explore these free sample topics:

Johns Hopkins Guides

-- The first section of this topic is shown below --


  • Aerobic, fastidious organism.
    • Organism lacks cell wall. Member of Mollicutes class, among the smallest known free-living bacteria.
    • Historically termed the "Eaton agent," prior to successful cultivation in 1962.
  • Believed to be a frequent cause of atypical pneumonia but diagnosis often difficult and serology inaccurate often.
    • Not a part of normal human oropharyngeal flora.
    • M. pneumoniae culture difficult. Growth often requires 7-21 days, successful in 40-90% of cases.
      • Culture media requires heart infusion, peptone, yeast extract, salts, glucose or arginine + fetal calf serum (5-20%).
      • Bacterial overgrowth a common problem.
  • Erythromycin (macrolide) resistance is now described, and especially common in China (90% of isolates).
    • Outbreak investigations in U.S. have found macrolide resistance rates of 8-27%.

-- To view the remaining sections of this topic, please or purchase a subscription --

Last updated: May 30, 2016