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Mycobacterium avium-complex (MAC, MAI, non-HIV)

Mycobacterium avium-complex (MAC, MAI, non-HIV) is a topic covered in the Johns Hopkins ABX Guide.

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  • M. avium and M. intracellulare: slow-growing mycobacteria (10-21 days on solid media).
    • M. intracellulare: principally causes pulmonary disease.
    • M. avium: more likely to cause disseminated disease (among immunocompromised people).
    • M chimaera and several other sub-spp. also fits within MAC (see separate module).
  • Environmental sources, especially water, are the reservoir for most human infections.

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Last updated: May 4, 2019


Hoffmann, Christopher J. "Mycobacterium Avium-complex (MAC, MAI, Non-HIV)." Johns Hopkins ABX Guide, The Johns Hopkins University, 2019. Johns Hopkins Guide, www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540361/all/Mycobacterium_avium_complex__MAC__MAI__non_HIV_.
Hoffmann CJ. Mycobacterium avium-complex (MAC, MAI, non-HIV). Johns Hopkins ABX Guide. The Johns Hopkins University; 2019. https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540361/all/Mycobacterium_avium_complex__MAC__MAI__non_HIV_. Accessed July 18, 2019.
Hoffmann, C. J. (2019). Mycobacterium avium-complex (MAC, MAI, non-HIV). In Johns Hopkins ABX Guide. Available from https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540361/all/Mycobacterium_avium_complex__MAC__MAI__non_HIV_
Hoffmann CJ. Mycobacterium Avium-complex (MAC, MAI, Non-HIV) [Internet]. In: Johns Hopkins ABX Guide. The Johns Hopkins University; 2019. [cited 2019 July 18]. Available from: https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540361/all/Mycobacterium_avium_complex__MAC__MAI__non_HIV_.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC T1 - Mycobacterium avium-complex (MAC, MAI, non-HIV) ID - 540361 A1 - Hoffmann,Christopher,M.D., M.P.H. Y1 - 2019/05/04/ BT - Johns Hopkins ABX Guide UR - https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540361/all/Mycobacterium_avium_complex__MAC__MAI__non_HIV_ PB - The Johns Hopkins University DB - Johns Hopkins Guide DP - Unbound Medicine ER -