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    Morganella

    Valeria Fabre, M.D.
    Morganella is a topic covered in the Johns Hopkins ABX Guide.

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    MICROBIOLOGY

    • Facultative anaerobic Gram-negative rod.
      • Non-lactose fermenter in the same family as Proteus.
      • Environmentally ubiquitous, part of normal colonic flora.
      • "Urea splitter," but stones seen less frequently than Proteus due to less effective urease enzyme.
    • Morganella only has single member in its genus M. morganii, and two subspecies: M. morganii and M. sibonii, which differ only in trehalose fermentation.
    • Antimicrobial susceptibility:
      • Naturally resistant to penicillin, first-, second-generation cephalosporins, macrolides, sulfamethoxazole.
      • Beta-lactamase is inducible, chromosomal AmpC type.
      • Production of extended spectrum beta-lactamases, including carbapenemases Amber class B -such as New Delhi metallo-β-lactamase 1 (NDM-1)- and Amber class D -such as OXA-181- as well as fluoroquinolone resistance have been reported
      • Tigecycline not reliably effective due to ArcAB efflux pump, although may show synergy in vitro with other antimicrobials[6].

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    Last updated: April 5, 2016

    Citation

    Fabre, Valeria. "Morganella." Johns Hopkins ABX Guide, The Johns Hopkins University, 2016. Johns Hopkins Guide, www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540354/all/Morganella.
    Fabre V. Morganella. Johns Hopkins ABX Guide. The Johns Hopkins University; 2016. https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540354/all/Morganella. Accessed March 21, 2019.
    Fabre, V. (2016). Morganella. In Johns Hopkins ABX Guide. Available from https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540354/all/Morganella
    Fabre V. Morganella [Internet]. In: Johns Hopkins ABX Guide. The Johns Hopkins University; 2016. [cited 2019 March 21]. Available from: https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540354/all/Morganella.
    * Article titles in AMA citation format should be in sentence-case
    TY - ELEC T1 - Morganella ID - 540354 A1 - Fabre,Valeria,M.D. Y1 - 2016/04/05/ BT - Johns Hopkins ABX Guide UR - https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540354/all/Morganella PB - The Johns Hopkins University DB - Johns Hopkins Guide DP - Unbound Medicine ER -