Lymphadenopathy and Lymphadenitis
To view the entire topic, please log in or purchase a subscription.
Official website of the Johns Hopkins Antibiotic (ABX), HIV, Diabetes, and Psychiatry Guides, powered by Unbound Medicine. Johns Hopkins Guide App for iOS, iPhone, iPad, and Android included. Explore these free sample topics:
-- The first section of this topic is shown below --
PATHOGENS
- Lists below are by no means comprehensive but list commonly considered pathogens causing lymphadenopathy, as well as some non-infectious considerations.
- Acute generalized LN (presenting in two or more regional groups): HIV, syphilis, EBV, CMV, Toxoplasma, Brucella, cat scratch disease (Bartonella), sarcoid, lymphoma, Stills disease, inflammatory bowel disease, Whipple’s disease, hypersensitivity reaction.
- HAART-associated immune reconstitution syndrome in HIV+ pts (IRIS).
- Acute localized:
- Cervical: group A streptococci, EBV, TB, cat scratch disease (Bartonella), lymphoma, temporal arteritis, chronic fatigue syndrome.
- Pre-auricular: adenovirus, conjunctivitis, tularemia, Bartonella (Parinauds syndrome).
- Epitrochlear: hand infection (medial 3 fingers), syphilis.
- Inguinal: syphilis, herpes, chancroid, LGV, chancroid, HIV, tularemia, plague.
- Chronic generalized: syphilis, TB, histoplasmosis, cryptococcosis, chronic granulomatous disease (CGD), lymphoma, HIV, sarcoid, hyperthyroidism, posttransplant lymphoproliferative disorder.
- Chronic localized: TB, cryptococcus, histoplasmosis, cat scratch disease (Bartonella), lymphoma, metastatic cancer, Kikuchi-Fujimoto disease, Rosai-Dorman disease, Castleman’s disease (some HHV-8).
- Non-infectious: many conditions, but consider sarcoidosis, Kikuchi-Fujimoto disease (usually cervical LN), lymphoma, SLE, metastatic malignancy, Rosai-Dorman disease, Castleman’s disease (some HHV-8), reactive lymphoid hyperplasia (RLH), dermatopathic lymphadenitis (DLN), Kimura disease, and lymphadenopathy-associated with autoimmune and metabolic/storage disease.
- Other nodal entities could include lymph node infarction, foreign body reactions, drug reactions, extramedullary hematopoiesis.
-- To view the remaining sections of this topic, please log in or purchase a subscription --
PATHOGENS
- Lists below are by no means comprehensive but list commonly considered pathogens causing lymphadenopathy, as well as some non-infectious considerations.
- Acute generalized LN (presenting in two or more regional groups): HIV, syphilis, EBV, CMV, Toxoplasma, Brucella, cat scratch disease (Bartonella), sarcoid, lymphoma, Stills disease, inflammatory bowel disease, Whipple’s disease, hypersensitivity reaction.
- HAART-associated immune reconstitution syndrome in HIV+ pts (IRIS).
- Acute localized:
- Cervical: group A streptococci, EBV, TB, cat scratch disease (Bartonella), lymphoma, temporal arteritis, chronic fatigue syndrome.
- Pre-auricular: adenovirus, conjunctivitis, tularemia, Bartonella (Parinauds syndrome).
- Epitrochlear: hand infection (medial 3 fingers), syphilis.
- Inguinal: syphilis, herpes, chancroid, LGV, chancroid, HIV, tularemia, plague.
- Chronic generalized: syphilis, TB, histoplasmosis, cryptococcosis, chronic granulomatous disease (CGD), lymphoma, HIV, sarcoid, hyperthyroidism, posttransplant lymphoproliferative disorder.
- Chronic localized: TB, cryptococcus, histoplasmosis, cat scratch disease (Bartonella), lymphoma, metastatic cancer, Kikuchi-Fujimoto disease, Rosai-Dorman disease, Castleman’s disease (some HHV-8).
- Non-infectious: many conditions, but consider sarcoidosis, Kikuchi-Fujimoto disease (usually cervical LN), lymphoma, SLE, metastatic malignancy, Rosai-Dorman disease, Castleman’s disease (some HHV-8), reactive lymphoid hyperplasia (RLH), dermatopathic lymphadenitis (DLN), Kimura disease, and lymphadenopathy-associated with autoimmune and metabolic/storage disease.
- Other nodal entities could include lymph node infarction, foreign body reactions, drug reactions, extramedullary hematopoiesis.
There's more to see -- the rest of this topic is available only to subscribers.