Johns Hopkins ABX Guide
Linezolid
INDICATIONS
FDA
FDA
- Pneumonia, hospital-acquired caused by MRSA, MSSA, and S. pneumoniae.
- Generally reserved for MRSA.
- Community acquired pneumonia caused by S. pneumoniae and MSSA.
- Not a preferred agent for CAP.
- Infections due to vancomycin-resistant Enterococcus faecium (VRE), with or without concurrent bacteremia.
- Complicated and uncomplicated skin and skin structure infection including diabetic foot ulcers (without osteomyelitis).
NON-FDA APPROVED USES
NON-FDA APPROVED USES
- Vascular catheter associated sepsis
- Surgical wound infections
- Furuncle/carbuncle
- Cellulitis/erysipelas
- Osteomyelitis, acute (second-line agent)
- Osteomyelitis, chronic (second-line agent)
- Septic arthritis, community-acquired (limited data)
- Hardware associated septic arthritis (limited data)
- Tuberculosis
- Non-tubercular mycobacteria
- Nocardia
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Last updated: October 2, 2018
Citation
Dzintars, Kathryn, and Paul A Pham. "Linezolid." Johns Hopkins ABX Guide, The Johns Hopkins University, 2018. Johns Hopkins Guides, www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540316/11/Linezolid.
Dzintars K, Pham PA. Linezolid. Johns Hopkins ABX Guide. The Johns Hopkins University; 2018. https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540316/11/Linezolid. Accessed October 31, 2025.
Dzintars, K., & Pham, P. A. (2018). Linezolid. In Johns Hopkins ABX Guide. The Johns Hopkins University. https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540316/11/Linezolid
Dzintars K, Pham PA. Linezolid [Internet]. In: Johns Hopkins ABX Guide. The Johns Hopkins University; 2018. [cited 2025 October 31]. Available from: https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540316/11/Linezolid.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC
T1 - Linezolid
ID - 540316
A1 - Dzintars,Kathryn,Pharm.D., BCPS
AU - Pham,Paul,Pharm.D.
Y1 - 2018/10/02/
BT - Johns Hopkins ABX Guide
UR - https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540316/11/Linezolid
PB - The Johns Hopkins University
DB - Johns Hopkins Guides
DP - Unbound Medicine
ER -
