Lactobacillus

Paul Auwaerter, M.D., Emily Kendall, M.D.
Lactobacillus is a topic covered in the Johns Hopkins ABX Guide.

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MICROBIOLOGY

  • Gram-positive, facultative anaerobic (or microaerophilic) rod [Fig].
    • > 170 species are known.
  • Normal flora of the GI/GU tract.
  • Produces lactic acid from glycogen providing for a low vaginal pH.
  • Species often employed for the production of yogurt, cheese, wine and other fermented products.
  • Most are inherently resistant to vancomycin.
    • Lactobacilli are typically resistant to aminoglycosides, ciprofloxacin and metronidazole.
      • L. acidophilus are susceptible to both penicillin and vancomycin
      • L. rhamnosus, L. casei are resistant to metronidazole and vancomycin.

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Last updated: September 27, 2019