Johns Hopkins Antibiotic (ABX) GuideDiagnosisGenitourinary

Genital/Anogenital Warts

Michael Melia, M.D.
Genital/Anogenital Warts is a topic covered in the Johns Hopkins Antibiotic (ABX) Guide.

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  • The most common viral sexually transmitted infection.
  • All anogenital warts are caused by human papillomavirus (HPV) infection.
  • Most (>90%) anogenital warts are benign and caused by HPV subtypes 6 and 11, the "low risk" (for malignancy) HPV subtypes.
    • HPV subtypes 16 and 18, the most common "high risk" subtypes, cause ~70% of cervical cancers but usually do not cause warts
    • These other "intermediate risk" HPV subtypes, including 16, 18, 31, 33, and 35, are associated with high grade squamous intrathelial neoplasia (HG-SIL) and are occasionally found in warts, particularly in persons with concurrent HIV infection.
  • For additional non-genital wart information, see HPV module.

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Last updated: July 2, 2016