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Fever of Unknown Origin (FUO)

Fever of Unknown Origin (FUO) is a topic covered in the Johns Hopkins ABX Guide.

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  • Classic definition: (Petersdorf and Beson, Medicine, 1961[29])
    1. Fever > 38.3°C
    2. Illness > 3 weeks
    3. Negative evaluation with hospital workup for > 1 week
  • Modern definition:
    1. Temperature > 38.3°C for > 3 wks duration without a diagnosis despite 2 outpt visits or 3 hospital days

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Last updated: November 8, 2016


Bartlett, John G. "Fever of Unknown Origin (FUO)." Johns Hopkins ABX Guide, The Johns Hopkins University, 2016. Johns Hopkins Guide, www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540224/all/Fever_of_Unknown_Origin__FUO_.
Bartlett JG. Fever of Unknown Origin (FUO). Johns Hopkins ABX Guide. The Johns Hopkins University; 2016. https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540224/all/Fever_of_Unknown_Origin__FUO_. Accessed May 20, 2019.
Bartlett, J. G. (2016). Fever of Unknown Origin (FUO). In Johns Hopkins ABX Guide. Available from https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540224/all/Fever_of_Unknown_Origin__FUO_
Bartlett JG. Fever of Unknown Origin (FUO) [Internet]. In: Johns Hopkins ABX Guide. The Johns Hopkins University; 2016. [cited 2019 May 20]. Available from: https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540224/all/Fever_of_Unknown_Origin__FUO_.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC T1 - Fever of Unknown Origin (FUO) ID - 540224 A1 - Bartlett,John,M.D. Y1 - 2016/11/08/ BT - Johns Hopkins ABX Guide UR - https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540224/all/Fever_of_Unknown_Origin__FUO_ PB - The Johns Hopkins University DB - Johns Hopkins Guide DP - Unbound Medicine ER -