Cryptococcal Meningitis is a topic covered in the Johns Hopkins ABX Guide.

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PATHOGENS

  • Main human pathogen:
    • Cryptococcus neoformans (predominant)
      • Four serotypes (A to D) described based upon the capsule components.
      • Three varieties described as causing human disease C. neoformans v. neoformans (most common), v. gattii, and v. grubii (recently established).
    • C. gattii: unlike C. neoformans, is more commonly seen in healthy hosts.
      • Has reduced sensitivity to fluconazole and appears to be more virulent.

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Last updated: February 3, 2016

Citation

TY - ELEC T1 - Cryptococcal Meningitis ID - 540146 A1 - Bartlett,John,M.D. Y1 - 2016/02/03/ PB - Johns Hopkins ABX Guide UR - https://www.unboundmedicine.com/medline/view/Johns_Hopkins_ABX_Guide/540146/all/Cryptococcal_Meningitis ER -