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Cryptococcal Meningitis

Cryptococcal Meningitis is a topic covered in the Johns Hopkins ABX Guide.

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  • Main human pathogen:
    • Cryptococcus neoformans (predominant)
      • Four serotypes (A to D) described based upon the capsule components.
      • Three varieties described as causing human disease C. neoformans v. neoformans (most common), v. gattii, and v. grubii (recently established).
    • C. gattii: unlike C. neoformans, is more commonly seen in healthy hosts.
      • Has reduced sensitivity to fluconazole and appears to be more virulent.

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Last updated: February 3, 2016


Bartlett, John G. "Cryptococcal Meningitis." Johns Hopkins ABX Guide, The Johns Hopkins University, 2016. Johns Hopkins Guide, www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540146/all/Cryptococcal_Meningitis.
Bartlett JG. Cryptococcal Meningitis. Johns Hopkins ABX Guide. The Johns Hopkins University; 2016. https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540146/all/Cryptococcal_Meningitis. Accessed August 19, 2019.
Bartlett, J. G. (2016). Cryptococcal Meningitis. In Johns Hopkins ABX Guide. Available from https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540146/all/Cryptococcal_Meningitis
Bartlett JG. Cryptococcal Meningitis [Internet]. In: Johns Hopkins ABX Guide. The Johns Hopkins University; 2016. [cited 2019 August 19]. Available from: https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540146/all/Cryptococcal_Meningitis.
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