Coronavirus is a topic covered in the Johns Hopkins ABX Guide.

To view the entire topic, please or purchase a subscription.

Official website of the Johns Hopkins Antibiotic (ABX), HIV, Diabetes, and Psychiatry Guides, powered by Unbound Medicine. Johns Hopkins Guide App for iOS, iPhone, iPad, and Android included. Explore these free sample topics:

Johns Hopkins Guides

-- The first section of this topic is shown below --


  • Positive single-strand, enveloped RNA virus belonging to the family Coronaviridae.
  • Name derived from the Latin corona, meaning crown. Viral envelope under electron microscopy appears crown-like due to small bulbar projections formed by the viral spike (S) peplomers.
  • Virus common infection of birds and mammals causing gastroenteritis and respiratory infections.
  • Important structural proteins include spike (S), envelope (E), membrane (M) and nucleocapsid (N).
  • In humans, growing number of strains identified as causing human disease, with SARS and MERS-CoV coronaviruses causing most severe disease.
    • Alpha coronaviruses 229E and NL63
    • Beta coronaviruses OC43 and HKU1
    • SARS [See Severe Acute Respiratory Syndrome module for specific information].
      • SARS-associated coronavirus felt to be an animal virus, likely of bat origin.
      • Presumed hosts include civets, wild boars, muntjac deer, hares and pheasants.
      • Animal traders in China shown to have high prevalence of IgG antibodies to the SARS-CoV
    • MERS-CoV [Middle East Respiratory Syndrome--Coronavirus, originally called Human coronavirus EMC (hCoV-EMC], discovered in 2012 as cause of severe illness in Middle East]
      • Infections to date of respiratory nature, acquired in countries in or neighboring the Arabian Peninsula.
      • See MERS-CoV module for detailed information.

-- To view the remaining sections of this topic, please or purchase a subscription --

Last updated: January 31, 2016