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Clostridium tetani (Tetanus)

Paul Auwaerter, M.D.
Clostridium tetani (Tetanus) is a topic covered in the Johns Hopkins ABX Guide.

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MICROBIOLOGY

  • Gram-positive bacillus, obligate anaerobe.
  • Spore wide spread in soil and animal feces.
  • Rod-shaped appearance on gram stain often likened to drumsticks or tennis rackets.
  • Toxin, tetanospasmin, causes tetanus: unopposed muscle spasm, contraction due to interference of toxin with neurotransmitters (including GABA and glycine).

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Last updated: April 4, 2016

Citation

Auwaerter, Paul. "Clostridium Tetani (Tetanus)." Johns Hopkins ABX Guide, The Johns Hopkins University, 2016. Johns Hopkins Guide, www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540136/all/Clostridium_tetani__Tetanus_.
Auwaerter P. Clostridium tetani (Tetanus). Johns Hopkins ABX Guide. The Johns Hopkins University; 2016. https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540136/all/Clostridium_tetani__Tetanus_. Accessed July 18, 2019.
Auwaerter, P. (2016). Clostridium tetani (Tetanus). In Johns Hopkins ABX Guide. Available from https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540136/all/Clostridium_tetani__Tetanus_
Auwaerter P. Clostridium Tetani (Tetanus) [Internet]. In: Johns Hopkins ABX Guide. The Johns Hopkins University; 2016. [cited 2019 July 18]. Available from: https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540136/all/Clostridium_tetani__Tetanus_.
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TY - ELEC T1 - Clostridium tetani (Tetanus) ID - 540136 A1 - Auwaerter,Paul,M.D. Y1 - 2016/04/04/ BT - Johns Hopkins ABX Guide UR - https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540136/all/Clostridium_tetani__Tetanus_ PB - The Johns Hopkins University DB - Johns Hopkins Guide DP - Unbound Medicine ER -