Haemophilus ducreyi (Chancroid)

Susan Tuddenham, M.D., Noreen A. Hynes, M.D., M.P.H., D.T.M.&H.
Haemophilus ducreyi (Chancroid) is a topic covered in the Johns Hopkins ABX Guide.

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MICROBIOLOGY

  • Fastidious, facultative anaerobic Gram-negative coccobacillus [Fig 1].
    • Requires hemin (X factor) for growth but no requirement for NAD (V factor)
    • Three types of nutritionally enriched media are needed for growth.
  • Organism co-localizes with neutrophils and fibrin at the ulcerative stage of the disease.
  • Specific molecular techniques were used to identify the likely geographic origin of strains.

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MICROBIOLOGY

  • Fastidious, facultative anaerobic Gram-negative coccobacillus [Fig 1].
    • Requires hemin (X factor) for growth but no requirement for NAD (V factor)
    • Three types of nutritionally enriched media are needed for growth.
  • Organism co-localizes with neutrophils and fibrin at the ulcerative stage of the disease.
  • Specific molecular techniques were used to identify the likely geographic origin of strains.

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Last updated: March 5, 2022