Brucella Species

Paul G. Auwaerter, M.D., Jaffar A. Al-Tawfiq, M.D.
Brucella Species is a topic covered in the Johns Hopkins ABX Guide.

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MICROBIOLOGY

  • Aerobic, intraceullular Gram-negative coccobacilli [Fig 1] causing brucellosis.
  • Grows on a variety of media, usually within 24-48h of inoculation.
  • Zoonotic disease, most important species for human infections:
    • B. abortus (cattle, buffalo)
    • B. melitensis (goat, sheep, camel)
    • B.suis (swine, wild animals)
    • B. canis (dog)
    • Less common:
      • B. ovis (sheep)
      • B. neotomae (desert and wood rats)
      • Three marine species also described afflicting marine mammals (B. delphini, B. pinnipediae, B. cetaceae) have been described causing human disease.
  • Most human disease due to B. arbortus and B. melitensis.
    • There is a correlation between seroprevalence in animals and human cases.

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MICROBIOLOGY

  • Aerobic, intraceullular Gram-negative coccobacilli [Fig 1] causing brucellosis.
  • Grows on a variety of media, usually within 24-48h of inoculation.
  • Zoonotic disease, most important species for human infections:
    • B. abortus (cattle, buffalo)
    • B. melitensis (goat, sheep, camel)
    • B.suis (swine, wild animals)
    • B. canis (dog)
    • Less common:
      • B. ovis (sheep)
      • B. neotomae (desert and wood rats)
      • Three marine species also described afflicting marine mammals (B. delphini, B. pinnipediae, B. cetaceae) have been described causing human disease.
  • Most human disease due to B. arbortus and B. melitensis.
    • There is a correlation between seroprevalence in animals and human cases.

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Last updated: January 12, 2020