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Anthrax

Paul G. Auwaerter, M.D., John G. Bartlett, M.D.
Anthrax is a topic covered in the Johns Hopkins ABX Guide.

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PATHOGENS

  • Bacillus anthracis (Category A bio-terrorism agent)
  • Spore is primary infectious form.
  • Virulence factors:
    • Antiphagocytic capsule
    • Exotoxins: why anti-toxin therapies have been developed given the prominence of these toxins in causing illness.
      • Edema toxin (ET)
      • Lethal toxin (LT)
      • Protective antigen (PA) combines ET and LT and facilitates entry into cells and assists in downregulating immune responses.

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Last updated: March 5, 2019

Citation

Auwaerter, Paul G, and John G Bartlett. "Anthrax." Johns Hopkins ABX Guide, The Johns Hopkins University, 2019. Johns Hopkins Guide, www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540028/all/Anthrax.
Auwaerter PG, Bartlett JG. Anthrax. Johns Hopkins ABX Guide. The Johns Hopkins University; 2019. https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540028/all/Anthrax. Accessed June 18, 2019.
Auwaerter, P. G., & Bartlett, J. G. (2019). Anthrax. In Johns Hopkins ABX Guide. Available from https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540028/all/Anthrax
Auwaerter PG, Bartlett JG. Anthrax [Internet]. In: Johns Hopkins ABX Guide. The Johns Hopkins University; 2019. [cited 2019 June 18]. Available from: https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540028/all/Anthrax.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC T1 - Anthrax ID - 540028 A1 - Auwaerter,Paul,M.D. AU - Bartlett,John,M.D. Y1 - 2019/03/05/ BT - Johns Hopkins ABX Guide UR - https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540028/all/Anthrax PB - The Johns Hopkins University DB - Johns Hopkins Guide DP - Unbound Medicine ER -