Anthrax, cutaneous
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PATHOGENS
- Bacillus anthracis
- B. anthracis is a Gram-positive spore-forming bacillus that may remain stable in the environment for decades.
- On Gram stain, rods form filamentous-like strands [Fig 1].
- Pathogenesis results from spore entry via skin (cutaneous anthrax) or lungs (inhalation anthrax).
- The vegetative form causes disease due to toxin production: Protective antigen (PA) which combines with edema factor (EF) to form edema toxin (ET) and with PA to form lethal toxin (LT)
- B. anthracis is a Gram-positive spore-forming bacillus that may remain stable in the environment for decades.
-- To view the remaining sections of this topic, please log in or purchase a subscription --
PATHOGENS
- Bacillus anthracis
- B. anthracis is a Gram-positive spore-forming bacillus that may remain stable in the environment for decades.
- On Gram stain, rods form filamentous-like strands [Fig 1].
- Pathogenesis results from spore entry via skin (cutaneous anthrax) or lungs (inhalation anthrax).
- The vegetative form causes disease due to toxin production: Protective antigen (PA) which combines with edema factor (EF) to form edema toxin (ET) and with PA to form lethal toxin (LT)
- B. anthracis is a Gram-positive spore-forming bacillus that may remain stable in the environment for decades.
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