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Adenovirus is a topic covered in the Johns Hopkins ABX Guide.

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MICROBIOLOGY

  • Non-enveloped double-stranded DNA virus.
    • There are 7 human species (A-G) and >60 types.[14]
    • Recent outbreaks linked to types 4, 7, and 14.[9]
  • Easily transmitted: aerosolized droplet, fecal-oral, waterborne, fomites and instruments.[6]
  • Persists in environment, may remain infectious at room temperature up to 3 wks.
  • Stable at low pH, resistant to gastric and biliary secretions.
    • Replicates to high viral load in gut. Can be asymptomatically shed.
    • Detection in stool often precedes detection in blood, GI tract may serve as reservoir for reactivation.[12]
    • Few serotypes, i.e., subgroup C, can induce latent infection in lymphoepithelial tissue.[1]

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Last updated: June 5, 2019

Citation

Spacek, Lisa A. "Adenovirus." Johns Hopkins ABX Guide, The Johns Hopkins University, 2019. Johns Hopkins Guide, www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540009/all/Adenovirus.
Spacek LA. Adenovirus. Johns Hopkins ABX Guide. The Johns Hopkins University; 2019. https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540009/all/Adenovirus. Accessed July 17, 2019.
Spacek, L. A. (2019). Adenovirus. In Johns Hopkins ABX Guide. Available from https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540009/all/Adenovirus
Spacek LA. Adenovirus [Internet]. In: Johns Hopkins ABX Guide. The Johns Hopkins University; 2019. [cited 2019 July 17]. Available from: https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540009/all/Adenovirus.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC T1 - Adenovirus ID - 540009 A1 - Spacek,Lisa,M.D., Ph.D. Y1 - 2019/06/05/ BT - Johns Hopkins ABX Guide UR - https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540009/all/Adenovirus PB - The Johns Hopkins University DB - Johns Hopkins Guide DP - Unbound Medicine ER -