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Actinomyces

Valeria Fabre, M.D., John G. Bartlett, M.D.
Actinomyces is a topic covered in the Johns Hopkins ABX Guide.

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MICROBIOLOGY

  • Thin, branching (filamentous or beaded) Gram-positive bacillus [Fig 1].
    • Microaerophilic, grow best anaerobically.
    • VERY fastidious, often does not grow in culture.
  • Agents: A. israelii, A. naeslundii, A. odontolyticus, A. viscosus, A. meyer and Propionibacterium propionicum and A. gereneseriae.
    • Virtually all cases are mixed infections with other bacteria including Eikenella corrodens, Bacteroides spp, S. aureus, Streptococcus spp., Aggregatibacter actinomycetemcomitans, and/or Fusobacterium sp.
    • Normal flora of mouth, gut, genital tract.
  • Diagnosis is often made by histopathology -- not by culture, even when suspected.

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Last updated: December 6, 2018

Citation

Fabre, Valeria, and John G Bartlett. "Actinomyces." Johns Hopkins ABX Guide, The Johns Hopkins University, 2018. Johns Hopkins Guide, www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540005/all/Actinomyces.
Fabre V, Bartlett JG. Actinomyces. Johns Hopkins ABX Guide. The Johns Hopkins University; 2018. https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540005/all/Actinomyces. Accessed May 19, 2019.
Fabre, V., & Bartlett, J. G. (2018). Actinomyces. In Johns Hopkins ABX Guide. Available from https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540005/all/Actinomyces
Fabre V, Bartlett JG. Actinomyces [Internet]. In: Johns Hopkins ABX Guide. The Johns Hopkins University; 2018. [cited 2019 May 19]. Available from: https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540005/all/Actinomyces.
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TY - ELEC T1 - Actinomyces ID - 540005 A1 - Fabre,Valeria,M.D. AU - Bartlett,John,M.D. Y1 - 2018/12/06/ BT - Johns Hopkins ABX Guide UR - https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540005/all/Actinomyces PB - The Johns Hopkins University DB - Johns Hopkins Guide DP - Unbound Medicine ER -