Johns Hopkins ABX Guide
Acanthamoeba
Acanthamoeba is a topic covered in the Johns Hopkins ABX Guide.
To view the entire topic, please sign in or purchase a subscription.
Official website of the Johns Hopkins Antibiotic (ABX), HIV, Diabetes, and Psychiatry Guides, powered by Unbound Medicine. Johns Hopkins Guide App for iOS, iPhone, iPad, and Android included. Explore these free sample topics:
-- The first section of this topic is shown below --
MICROBIOLOGY
- Free-living amoeba, ubiquitous, and can be isolated worldwide from soil, air, and fresh- and saltwater.
- See also N. fowleri. for details on this organism.
- Eukaryotic, shares homologies with mammalian cells.[10]
- Life cycle consists of 2 stages: mobile trophozoite, the infective stage, is 14-40 um in diameter, and the dormant cyst is double-walled and wrinkled.
- The cyst is resistant to chlorine and antibiotics. Encystation occurs under stress.
- The transition from cyst to trophozoite occurs optimally in vitro at 30°C or 86°F.[6]
- Described as “Trojan horses” because acanthamoebae can harbor intracellular bacteria.[12]
- Treatment of bacterial endosymbionts may attenuate inflammation associated with acanthamoebae infection.[7]
-- To view the remaining sections of this topic, please sign in or purchase a subscription --
MICROBIOLOGY
- Free-living amoeba, ubiquitous, and can be isolated worldwide from soil, air, and fresh- and saltwater.
- See also N. fowleri. for details on this organism.
- Eukaryotic, shares homologies with mammalian cells.[10]
- Life cycle consists of 2 stages: mobile trophozoite, the infective stage, is 14-40 um in diameter, and the dormant cyst is double-walled and wrinkled.
- The cyst is resistant to chlorine and antibiotics. Encystation occurs under stress.
- The transition from cyst to trophozoite occurs optimally in vitro at 30°C or 86°F.[6]
- Described as “Trojan horses” because acanthamoebae can harbor intracellular bacteria.[12]
- Treatment of bacterial endosymbionts may attenuate inflammation associated with acanthamoebae infection.[7]
There's more to see -- the rest of this entry is available only to subscribers.
Last updated: December 9, 2019
Citation
Spacek, Lisa A. "Acanthamoeba." Johns Hopkins ABX Guide, The Johns Hopkins University, 2019. Johns Hopkins Guide, www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540002/all/Acanthamoeba.
Spacek LA. Acanthamoeba. Johns Hopkins ABX Guide. The Johns Hopkins University; 2019. https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540002/all/Acanthamoeba. Accessed January 28, 2020.
Spacek, L. A. (2019). Acanthamoeba. In Johns Hopkins ABX Guide. Available from https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540002/all/Acanthamoeba
Spacek LA. Acanthamoeba [Internet]. In: Johns Hopkins ABX Guide. The Johns Hopkins University; 2019. [cited 2020 January 28]. Available from: https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540002/all/Acanthamoeba.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC
T1 - Acanthamoeba
ID - 540002
A1 - Spacek,Lisa,M.D., Ph.D.
Y1 - 2019/12/09/
BT - Johns Hopkins ABX Guide
UR - https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540002/all/Acanthamoeba
PB - The Johns Hopkins University
DB - Johns Hopkins Guide
DP - Unbound Medicine
ER -