Acanthamoeba
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MICROBIOLOGY
- Free-living amoeba, ubiquitous, and can be isolated worldwide from soil, air, and fresh- and saltwater.
- See also N. fowleri. for details on this organism.
- Eukaryotic, shares homologies with mammalian cells.[10]
- Life cycle consists of 2 stages: mobile trophozoite, the infective stage, is 14-40 um in diameter, and the dormant cyst is double-walled and wrinkled.
- The cyst is resistant to chlorine and antibiotics. Encystation occurs under stress.
- The transition from cyst to trophozoite occurs optimally in vitro at 30°C or 86°F.[6]
- Described as “Trojan horses” because acanthamoebae can harbor intracellular bacteria.[12]
- Treatment of bacterial endosymbionts may attenuate inflammation associated with acanthamoebae infection.[7]
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MICROBIOLOGY
- Free-living amoeba, ubiquitous, and can be isolated worldwide from soil, air, and fresh- and saltwater.
- See also N. fowleri. for details on this organism.
- Eukaryotic, shares homologies with mammalian cells.[10]
- Life cycle consists of 2 stages: mobile trophozoite, the infective stage, is 14-40 um in diameter, and the dormant cyst is double-walled and wrinkled.
- The cyst is resistant to chlorine and antibiotics. Encystation occurs under stress.
- The transition from cyst to trophozoite occurs optimally in vitro at 30°C or 86°F.[6]
- Described as “Trojan horses” because acanthamoebae can harbor intracellular bacteria.[12]
- Treatment of bacterial endosymbionts may attenuate inflammation associated with acanthamoebae infection.[7]
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