Medication-Induced Disorders / Side Effects

Colleen Ohm, PA-C, Thomas W. Sedlak, M.D., Ph.D.


  • Antidepressant discontinuation syndrome
    • Set of symptoms that can occur after abrupt cessation (or marked reduction in dose) of an antidepressant taken continuously for at least 1 month
  • Neuroleptic-induced Parkinsonism and other medication-induced Parkinsonism
    • Parkinsonian symptoms of mask-like facies, resting tremor, cogwheel rigidity, shuffling gait, and psychomotor retardation (bradykinesia) caused by antipsychotic or other medications
  • Neuroleptic malignant syndrome
    • Life-threatening emergency associated with the use of neuroleptic agents and characterized by a distinctive clinical syndrome of mental status change, rigidity, fever, and autonomic instability
  • Medication-induced acute dystonia
    • Involuntary contractions of major muscle groups, characterized by symptoms such as torticollis, retrocollis, oculogyric crisis, and opisthotonos
  • Medication-induced acute akathisia
    • Motor restlessness with a compelling urge to move and an inability to sit still
  • Tardive dyskinesia
    • Hyperkinetic movement disorder that appears with a delayed onset after prolonged use of dopamine receptor blocking agents (e.g., neuroleptics)
  • Tardive dystonia and tardive akathisia
    • Delayed onset of involuntary contractions of muscle groups (tardive dystonia) or motor restlessness (tardive akathisia)
  • Medication-induced postural tremor
    • Tremor that occurs when one tries to hold a body part still, against the force of gravity
  • Other medication-induced movement disorder
    • Medication-induced movement disorders not described above

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Last updated: May 2, 2017