Doxycycline
INDICATIONS
FDA
FDA
- Acne vulgaris
- Adjunctive therapy if severe
- Amebiasis
- Adjunctive therapy
- Anthrax due to Bacillus anthracis
- Inhalation anthrax: Post-exposure prophylaxis or treatment (see "biodefense-anthrax")
- Treatment of cutaneous, gastrointestinal or oropharyngeal anthrax
- If PCN allergic
- Uncomplicated gonorrhea caused by Neisseria gonorrhoeae
- Syphilis caused by Treponema pallidum
- Yaws caused by Treponema pertenue
- Listeriosis due to Listeria monocytogenes
- Vincent’s infection caused by Fusobacterium nucleatum subsp fusiforme
- Actinomycosis caused by Actinomyces israelii
- Infections caused by Clostridia species
- Relapsing fever caused by Borrelia recurrentis
- Respiratory infections
- Mycoplasma pneumonia
- Psittacosis caused by Chlamydia psittaci
- Infections when caused by the following bacteria with appropriate susceptibility
- Rickettsial infections
- Rocky Mountain spotted fever (RMSF), typhus, Q fever, rickettsialpox, and tick fevers caused by Rickettsia species.
- Sexually Transmitted Infections
- Uncomplicated urethral, endocervical or rectal infections caused by Chlamydia trachomatis
- Nongonococcal urethritis caused by Ureaplasma urealyticum
- Lymphogranuloma venereum caused by Chlamydia spp.
- Granuloma inguinale caused by Calymmatobacterium granulomatis
- Trachoma, inclusion conjunctivitis caused by C. trachomatis.
- Gram-negative infections caused by Y. pestis, F. tularensis, V. cholerae, C. fetus, Brucella spp., B. bacilliformis, C. granulomatis.
- And for other organisms, if susceptible: Escherichia coli, Enterobacter aerogenes, Shigella species, Acinetobacter species
- Urinary tract infections caused by Klebsiella species
- Malaria
- Prophylaxis due to P. falciparum for short-term (< 4 months) travelers to regions with chloroquine and/or pyrimethamine-sulfadoxine-resistant strains.
NON-FDA APPROVED USES
NON-FDA APPROVED USES
- Lyme disease
- Community-acquired pneumonia
- Acute bacterial rhinosinusitis
- Skin and soft tissue infections due to S. aureus
- Tularemia
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Last updated: September 13, 2023
Citation
Dzintars, Kathryn, and Paul A Pham. "Doxycycline." Johns Hopkins HIV Guide, 2023. Johns Hopkins Guides, www.hopkinsguides.com/hopkins/view/Johns_Hopkins_HIV_Guide/545264/all/Doxycycline.
Dzintars K, Pham PA. Doxycycline. Johns Hopkins HIV Guide. 2023. https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_HIV_Guide/545264/all/Doxycycline. Accessed September 22, 2023.
Dzintars, K., & Pham, P. A. (2023). Doxycycline. In Johns Hopkins HIV Guide https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_HIV_Guide/545264/all/Doxycycline
Dzintars K, Pham PA. Doxycycline [Internet]. In: Johns Hopkins HIV Guide. ; 2023. [cited 2023 September 22]. Available from: https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_HIV_Guide/545264/all/Doxycycline.
* Article titles in AMA citation format should be in sentence-case
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