- Initial episode of herpes genitalis (immunocompromised pts)
- Herpes simplex encephalitis (immunocompetent pts)
- Herpes zoster
- Treatment of varicella in immunocompetent pts when started within 24 hrs of onset of typical chickenpox rash (American Academy of Pediatrics does not recommend its use for treatment of uncomplicated chickenpox in healthy children)
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