Sulfadiazine is a topic covered in the Johns Hopkins HIV Guide.

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  • CNS and ocular toxoplasmosis (in combination with pyrimethamine); nocardiosis.
  • Malaria due to chloroquine-resistant P. falciparum malaria (in combination with quinine and pyrimethamine).
  • UTI (also FDA indicated for pyelonephritis, but generally reserved for uncomplicated UTI). Sulfamethoxazole preferred.
  • FDA indicated, but not generally recommended: Chancroid; trachoma; inclusion conjunctivitis.
  • FDA indicated, but not generally recommended: Prophylaxis of meningococcal meningitis when sulfonamide-sensitive group A strains known to prevail; meningococcal meningitis; acute otitis media due to H. influenzae (in combination with PCN); prophylaxis against recurrences of rheumatic fever (alternative to penicillin); H. influenzae meningitis (in combination with streptomycin)

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Last updated: February 26, 2011