Penicillium marneffei is a topic covered in the Johns Hopkins HIV Guide.

To view the entire topic, please or purchase a subscription.

Official website of the Johns Hopkins Antibiotic (ABX), HIV, Diabetes, and Psychiatry Guides, powered by Unbound Medicine. Johns Hopkins Guide App for iOS, iPhone, iPad, and Android included. Explore these free sample topics:

Johns Hopkins Guides

-- The first section of this topic is shown below --


  • Dimorphic fungus, recent taxonomy change to Talaromyces from Penicillium subgenus Biverticillium, reflects phylogenetic distinction from other subgenera of Penicillium.
    • Mold at 25oC with short, hyaline, septate and branched hyphae;
    • Yeast at 37oC with cerebriform, smooth, light tan colonies; secretes bright red pigment that appears pink as it diffuses into agar.
      • Yeast form 3-6 x 2 µm, sausage-shaped with central transverse septum.
  • Reservoir: Bamboo rats
    • T. marneffei geographically distributed across tropical SE Asia.[10]
    • Found in 100% of sample of hoary bamboo rats (cultured from lungs, liver and spleen) in Guangxi Province, China.[11]
    • Organism also isolated from soil of bamboo rats’ burrows.
  • Transmitted primarily via inhalation; also direct inoculation, possibly ingestion.
  • Endemic in: NE India, Thailand, Vietnam, Indonesia, Hong Kong, southern China.

-- To view the remaining sections of this topic, please or purchase a subscription --

Last updated: October 3, 2015