Ciprofloxacin is a topic covered in the Johns Hopkins HIV Guide.

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  • Uncomplicated UTI (ciprofloxacin XR and ciprofloxacin), complicated UTI (ciprofloxacin).
  • Post-exposure prophylaxis for inhalation anthrax. CDC recommends as first line agent + 1-2 additional agent(s) with in vitro activity (for inhalation anthrax, see "biodefense-anthrax" module).
  • Complicated intra-abdominal infections (in combination with metronidazole)
  • Infectious diarrhea
  • Endocervical and urethral infections caused N. gonorrhoeae (high resistance rates reported in Hawaii and California).
  • Empiric therapy for neutropenic fever (in combination with piperacillin); typhoid fever
  • Nosocomial pneumonia
  • Prostatitis
  • Acute sinusitis
  • Skin and soft tissue infections; bone and joint infections 11) bacterial conjunctivitis (ophthalmic ointment) 12) bacterial conjuctivitis and corneal ulcers (ophthalmic solution) 13) Acute otitis externa (otic suspension)


  • Tuberculosis, MAC and other atypical mycobacterial infections (2nd or 3rd line)

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Last updated: December 22, 2011