Sofosbuvir + Ledipasvir

Janessa M. Smith, PharmD, BCPS
Sofosbuvir + Ledipasvir is a topic covered in the Johns Hopkins ABX Guide.

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INDICATIONS

FDA

  • Treatment of chronic hepatitis C virus (HCV) genotype 1, 4, 5 or 6 infection.
    • Indicated for treatment of HCV infection in treatment-experienced patients without cirrhosis and with compensated cirrhosis (Child-Pugh A) or decompensated cirrhosis (Child-Pugh B or C)
    • Treatment-naïve patients with compensated cirrhosis (Child-Pugh A) or decompensated cirrhosis (Child-Pugh B or C), and liver transplant recipients.

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INDICATIONS

FDA

  • Treatment of chronic hepatitis C virus (HCV) genotype 1, 4, 5 or 6 infection.
    • Indicated for treatment of HCV infection in treatment-experienced patients without cirrhosis and with compensated cirrhosis (Child-Pugh A) or decompensated cirrhosis (Child-Pugh B or C)
    • Treatment-naïve patients with compensated cirrhosis (Child-Pugh A) or decompensated cirrhosis (Child-Pugh B or C), and liver transplant recipients.

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Last updated: July 31, 2016