Official website of the Johns Hopkins Antibiotic (ABX), HIV, Diabetes, and Psychiatry Guides, powered by Unbound Medicine. Johns Hopkins Guide App for iOS, iPhone, iPad, and Android included. Explore these free sample topics:
-- The first section of this topic is shown below --
- Gonococcal urethritis:5-20%
- Neisseria gonorrhoeae: 5-20% of urethritis in the U.S. (higher in inner-city populations).
- Non-gonococcal urethritis:
- Chlamydia trachomatis (CT): the most frequent cause of urethritis in men accounting for 23%-55% of cases. However, the proportion of non-gonococcal urethritis (NGU) cases due to CT is declining gradually.
- Mycoplasma genitalium: maybe the second most frequent cause of urethritis in the U.S and U.K. May account for between 15%-22% of cases of acute NGU. Also has a role in chronic NGU.
- Trichomonas vaginalis: is the cause of only about 2% of cases of acute NGU but probably a higher proportion of chronic NGU.
- Ureaplasma urealyticum: biovar 2 is probably a more important cause of acute NGU than previously realized. Note that organism can be cultured from 30-40% of asymptomatic men. Quantification of the organism may help establish a diagnosis (Frolund Sex Transm Infect 2011).
- Less common: include
- Herpes simplex virus (rare in absence of obvious skin lesions)
- Haemophilus spp
- Yeasts, e.g., Candida spp.
- N. meningitidis
- Staphylococcus saprophyticus.
- Novel bacteria recently associated with bacterial vaginosis such as Leptotrichia/Sneathia spp. may be the urethral pathogens of "idiopathic" NGU.