Trichomonas vaginalis

Trichomonas vaginalis is a topic covered in the Johns Hopkins ABX Guide.

To view the entire topic, please or .

Official website of the Johns Hopkins Antibiotic (ABX), HIV, Diabetes, and Psychiatry Guides, powered by Unbound Medicine. Johns Hopkins Guide App for iOS, iPhone, iPad, and Android included. Explore these free sample topics:

-- The first section of this topic is shown below --

MICROBIOLOGY

  • Trichomonas vaginalis (TV): 5-15 µm, pear-shaped, motile, flagellated protozoan parasite.
    • Exists in the trophozoite stage only [Fig. 1; life cycle].
      • Facultative anaerobe divides by binary fission.
      • Optimal growth in moist milieu at a pH of 4.9-7.5 and a temperature of 35oC-37oC.
    • Trichomonads gather in clusters on the stratified urogenital epithelium, covering only a small surface area.
      • Parasites invade the superficial epithelium causing damage directly beneath the clustered trichomonads.
      • The nonspecific inflammatory response was noted in the lamina propria with plasma cells, lymphocytes, and neutrophils present.
      • Superficial ulceration of the epithelium can occur.
  • Transmission issues:
    • Can survive up to 45 minutes on clothing, washcloths, and in bathwater.
    • The presence of infection enhances the acquisition of HIV infection.
    • Antecedent bacterial vaginosis (BV), is a risk factor for T. vaginalis acquisition.

-- To view the remaining sections of this topic, please or --

MICROBIOLOGY

  • Trichomonas vaginalis (TV): 5-15 µm, pear-shaped, motile, flagellated protozoan parasite.
    • Exists in the trophozoite stage only [Fig. 1; life cycle].
      • Facultative anaerobe divides by binary fission.
      • Optimal growth in moist milieu at a pH of 4.9-7.5 and a temperature of 35oC-37oC.
    • Trichomonads gather in clusters on the stratified urogenital epithelium, covering only a small surface area.
      • Parasites invade the superficial epithelium causing damage directly beneath the clustered trichomonads.
      • The nonspecific inflammatory response was noted in the lamina propria with plasma cells, lymphocytes, and neutrophils present.
      • Superficial ulceration of the epithelium can occur.
  • Transmission issues:
    • Can survive up to 45 minutes on clothing, washcloths, and in bathwater.
    • The presence of infection enhances the acquisition of HIV infection.
    • Antecedent bacterial vaginosis (BV), is a risk factor for T. vaginalis acquisition.

There's more to see -- the rest of this entry is available only to subscribers.

Last updated: November 14, 2021