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- Polymicrobial in up to 25% including anaerobes.
- Given that most splenic abscesses are secondary to bacteremia or fungemia (e.g., associated with endocarditis, UTI, pancreatitis, GI tract, etc.), the likely pathogen(s) are determined by original focus.
- Gram-negative bacilli, especially
- Staphylococcus aureus
- Candida spp.
- Neutropenia and chronic corticosteroid use predispose to candidal splenic abscesses.
- Chronic disseminated candidiasis (formerly hepatosplenic candidiasis) often include frank candidal splenic abscesses.
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Last updated: September 3, 2017
Carpenter, Christopher F, and Nick Gilpin. "Splenic Abscess." Johns Hopkins ABX Guide, The Johns Hopkins University, 2017. Johns Hopkins Guide, www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540514/all/Splenic_Abscess.
Carpenter CF, Gilpin N. Splenic Abscess. Johns Hopkins ABX Guide. The Johns Hopkins University; 2017. https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540514/all/Splenic_Abscess. Accessed December 5, 2019.
Carpenter, C. F., & Gilpin, N. (2017). Splenic Abscess. In Johns Hopkins ABX Guide. Available from https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540514/all/Splenic_Abscess
Carpenter CF, Gilpin N. Splenic Abscess [Internet]. In: Johns Hopkins ABX Guide. The Johns Hopkins University; 2017. [cited 2019 December 05]. Available from: https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540514/all/Splenic_Abscess.
TY - ELEC
T1 - Splenic Abscess
ID - 540514
A1 - Carpenter,Christopher,M.D.
AU - Gilpin,Nick,D.O.
Y1 - 2017/09/03/
BT - Johns Hopkins ABX Guide
UR - https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540514/all/Splenic_Abscess
PB - The Johns Hopkins University
DB - Johns Hopkins Guide
DP - Unbound Medicine