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Other atypical mycobacteria

Other atypical mycobacteria is a topic covered in the Johns Hopkins ABX Guide.

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MICROBIOLOGY

  • M. celatum: slow growing (3-8 wks to culture), non-photochromogenic.
    • May cause false positive M. tuberculosis direct (MTD) test or ribosomal RNA test.
    • Found widely in the environment (soil, water, dust).
  • M. genavense: very slow grower (42d average); difficult to grow; alert lab if M. genavense suspected.
    • Consider if AFB growing poorly and Mtb, MAI probe negative.
    • Found in bird populations, ferrets.
    • Antimicrobial testing often problematic due to poor culture growth.
  • M. haemophilum: slow growing; alert lab if suspected since requires hemin or iron to grow in culture and grows best at 28-30°C.
  • M. malmoense: slow growing; most clinical isolates/reports from northern Europe.
  • M. mucogenicum: rapid grower (< 7 days in culture); sporadic contaminant in respiratory samples; water is the environmental reservoir.
    • Previously known as M. chelonae-like organism.
  • M. simiae: growth may take 4-6 weeks on LJ slants.
  • M. szulgai: scotochromogen at 37ºC, and a photochromogen at 25ºC.

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Last updated: May 5, 2019

Citation

Auwaerter, Paul. "Other Atypical Mycobacteria." Johns Hopkins ABX Guide, The Johns Hopkins University, 2019. Johns Hopkins Guide, www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540406/all/Other_atypical_mycobacteria.
Auwaerter P. Other atypical mycobacteria. Johns Hopkins ABX Guide. The Johns Hopkins University; 2019. https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540406/all/Other_atypical_mycobacteria. Accessed July 20, 2019.
Auwaerter, P. (2019). Other atypical mycobacteria. In Johns Hopkins ABX Guide. Available from https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540406/all/Other_atypical_mycobacteria
Auwaerter P. Other Atypical Mycobacteria [Internet]. In: Johns Hopkins ABX Guide. The Johns Hopkins University; 2019. [cited 2019 July 20]. Available from: https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540406/all/Other_atypical_mycobacteria.
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TY - ELEC T1 - Other atypical mycobacteria ID - 540406 A1 - Auwaerter,Paul,M.D. Y1 - 2019/05/05/ BT - Johns Hopkins ABX Guide UR - https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540406/all/Other_atypical_mycobacteria PB - The Johns Hopkins University DB - Johns Hopkins Guide DP - Unbound Medicine ER -