Metronidazole
Metronidazole is a topic covered in the Johns Hopkins ABX Guide.
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INDICATIONS
FDA
FDA
- Anaerobic infections: intra-abdominal infections, skin and skin structure infections, bone and joint infections
- Bacterial septicemia; endocarditis (caused by Bacteroides spp.)
- Gynecologic infections (endometritis, endomyometritis, tubo-ovarian abscess, and postsurgical vaginal cuff infection) in combination with agents active against Gram-negative urogenital flora.
- Lower respiratory tract infections (in combination with another agent with activity against microaerophilic Streptococcus)
- Adjunct treatment for gastritis and duodenal ulcer associated with Helicobacter pylori
- CNS infections (meningitis and brain abscess)
- Treatment of acute intestinal amebiasis and amebic liver abscess
- Treatment of symptomatic and asymptomatic trichomoniasis
- Bacterial vaginosis (vaginal gel)
- Acne rosacea (topical gel)
NON-FDA APPROVED USES
NON-FDA APPROVED USES
- Colitis, including C. difficile, Crohn’s flare
- Treatment of giardiasis and dracunculiasis
- Periodontal disease
- Elective colorectal surgery (classified as contaminated or potentially contaminated)
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INDICATIONS
FDA
FDA
- Anaerobic infections: intra-abdominal infections, skin and skin structure infections, bone and joint infections
- Bacterial septicemia; endocarditis (caused by Bacteroides spp.)
- Gynecologic infections (endometritis, endomyometritis, tubo-ovarian abscess, and postsurgical vaginal cuff infection) in combination with agents active against Gram-negative urogenital flora.
- Lower respiratory tract infections (in combination with another agent with activity against microaerophilic Streptococcus)
- Adjunct treatment for gastritis and duodenal ulcer associated with Helicobacter pylori
- CNS infections (meningitis and brain abscess)
- Treatment of acute intestinal amebiasis and amebic liver abscess
- Treatment of symptomatic and asymptomatic trichomoniasis
- Bacterial vaginosis (vaginal gel)
- Acne rosacea (topical gel)
NON-FDA APPROVED USES
NON-FDA APPROVED USES
- Colitis, including C. difficile, Crohn’s flare
- Treatment of giardiasis and dracunculiasis
- Periodontal disease
- Elective colorectal surgery (classified as contaminated or potentially contaminated)
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Last updated: January 12, 2020
Citation
Dzintars, Kathryn, and Paul A Pham. "Metronidazole." Johns Hopkins ABX Guide, The Johns Hopkins University, 2020. Johns Hopkins Guides, www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540346/7/Metronidazole.
Dzintars K, Pham PA. Metronidazole. Johns Hopkins ABX Guide. The Johns Hopkins University; 2020. https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540346/7/Metronidazole. Accessed March 21, 2023.
Dzintars, K., & Pham, P. A. (2020). Metronidazole. In Johns Hopkins ABX Guide. The Johns Hopkins University. https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540346/7/Metronidazole
Dzintars K, Pham PA. Metronidazole [Internet]. In: Johns Hopkins ABX Guide. The Johns Hopkins University; 2020. [cited 2023 March 21]. Available from: https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540346/7/Metronidazole.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC
T1 - Metronidazole
ID - 540346
A1 - Dzintars,Kathryn,Pharm.D., BCPS
AU - Pham,Paul,Pharm.D.
Y1 - 2020/01/12/
BT - Johns Hopkins ABX Guide
UR - https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540346/7/Metronidazole
PB - The Johns Hopkins University
DB - Johns Hopkins Guides
DP - Unbound Medicine
ER -