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- Acid-fast bacillus (AFB) morphologically resembles tubercle bacillus.
- M. leprae seen worldwide, but most common in Asia, Central and South America. Brazil, India, and Indonesia contribute 80% to the global new caseload.
- Newly identified species M. lepromatosis sp nov has been proposed as causing disseminated leprosy.
- Slow-growing. Obligate intracellular pathogen, average doubling time ~2 weeks. Cannot culture in the microbiology lab.
- Armadillos and immunocompromised mice used to grow M. leprae for research purposes.
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Last updated: December 8, 2019
Auwaerter, Paul G, and Valeria Fabre. "Mycobacterium Leprae." Johns Hopkins ABX Guide, The Johns Hopkins University, 2019. Johns Hopkins Guide, www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540310/all/Mycobacterium_leprae.
Auwaerter PG, Fabre V. Mycobacterium leprae. Johns Hopkins ABX Guide. The Johns Hopkins University; 2019. https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540310/all/Mycobacterium_leprae. Accessed December 14, 2019.
Auwaerter, P. G., & Fabre, V. (2019). Mycobacterium leprae. In Johns Hopkins ABX Guide. Available from https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540310/all/Mycobacterium_leprae
Auwaerter PG, Fabre V. Mycobacterium Leprae [Internet]. In: Johns Hopkins ABX Guide. The Johns Hopkins University; 2019. [cited 2019 December 14]. Available from: https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540310/all/Mycobacterium_leprae.
TY - ELEC
T1 - Mycobacterium leprae
ID - 540310
A1 - Auwaerter,Paul,M.D.
AU - Fabre,Valeria,M.D.
Y1 - 2019/12/08/
BT - Johns Hopkins ABX Guide
UR - https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540310/all/Mycobacterium_leprae
PB - The Johns Hopkins University
DB - Johns Hopkins Guide
DP - Unbound Medicine